Roscosmos has announced the crew compositions of the expeditions to the International Space Station for 2021–2023. The commanders and spaceflight participants of the prime and backup crews that will launch to the station within the scientific and educational project ‘Challenge’, have also been officially confirmed. The corresponding decision was signed by Roscosmos Director General Dmitry Rogozin.

Participants of the joint project of Roscosmos and Channel One Klim Shipenko and Yulia Peresild have been included in the ISS-66 expedition prime crew, with Roscosmos cosmonaut Anton Shkaplerov as their spacecraft commander (and the ISS-66 flight engineer). Their backups are Alexey Dudin and Alyona Mordovina, as well as Oleg Artemyev as their commander (and ISS-66 flight engineer). The start of the crewed vehicle is scheduled for October 2021.

Prior to that, the start of EP-20 preflight preparations of two space tourists had been announced with Yusaku Maezawa and Yozo Hirano to travel to the International Space Station in December this year with the spacecraft commander Roscosmos cosmonaut Alexander Misurkin and Alexander Skvortsov as his backup.

In 2022, Roscosmos cosmonauts Oleg Artemyev, Denis Matveyev and Sergey Korsakov were confirmed as the 67th long-term expedition crew and Sergey Prokopiev, Anna Kikina and Dmitry Petelin as their backups. For the first time after a long break, a Russian woman, Roscosmos cosmonaut Anna Kikina will become the ISS crewmember of the 68th expedition, scheduled for autumn 2022 - spring 2023. She will launch to the station with cosmonauts Sergey Prokopiev and Dmitry Petelin. Oleg Kononenko, Nikolay Chub and Andrey Fedyaev will be their backups during the preparation. In the second half of 2023, as part of the ISS-69 expedition, Oleg Kononenko, Nikolay Chub and Andrey Fedyaev have been appointed as the prime crew of the Russian segment of the ISS.